The contents of the curriculum update represent a concise overview of clinical trials in the emerging field of study relating to the endothelium and its role in cardiovascular health and disease.
There is no doubt that advances have been made in reducing the morbidity and mortality of coronary artery disease (CAD) through a focus on treating late manifestations of disease. The new area of scientific excitement examines one of the early manifestations of CAD - endothelial dysfunction.
This lecture material explores the following:
- Role of hypertension in endothelial impairment
- Effect of dyslipidemia on endothelial function
- Vasculoprotective effects of ACE inhibitors and HMG-CoA reductase inhibitors
- Recent clinical trials on the benefits of improving endothelial function
It is an exciting slide set that addresses not only the insults to the endothelium that may produce dysfunction but also discusses data from recent clinical trials that are pushing forward the boundaries of modern cardiovascular medicine.