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| Slide Lecture Programs |
| 2007 Core Curriculum |
| Myocardial Ischemia Redefined: Optimal Care in CAD |
October 9, 2007
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| III: |
Clinical Trial Update |
Slide 74 |
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COURAGE: Treatment effect on primary outcome
- As an initial management strategy in patients with stable CAD, PCI added to optimal medical therapy did not reduce the primary composite endpoint of death and nonfatal MI, or reduce major cardiovascular events, as compared with optimal therapy alone during follow-up.
- The primary outcome (a composite of death from any cause and nonfatal MI) occurred in 211 patients in the PCI group and 202 patients in the medical therapy group.
- The estimated 4.6-year cumulative primary-event rates were 19.0% in the PCI group and 18.5% in the medical-therapy group (unadjusted HR for the PCI group 1.05, 95% CI 0.87-1.27, P = 0.62).
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