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| Slide Lecture Programs |
| 2006 Core Curriculum |
| Antiplatelet Interventions in ACS |
March 10, 2006
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Clinical Insights, Risk Stratification, and Enhancing Outcomes
- An evaluation of data on >105,000 NSTE ACS patients in the CRUSADE quality improvement initiative showed that in-hospital mortality declined progressively with increasing use of Class I ACC/AHA recommended early cardiac care (medical acute [<24-hour] therapies, including aspirin, b-blockers, UFH/LMWH, GP IIb/IIIa inhibitors in patients undergoing catheterization and PCI, and clopidogrel in patients undergoing PCI; and catheterization and revascularization within 48 hours).
- The progressive reduction in mortality with increasing implementation of recommended treatment was consistent in older and younger patients (<75 vs >75 year of age).
- In the overall population, in-hospital mortality decreased 21% with each additional therapy (adjusted OR 0.79, 95% CI 0.77--{0.82).
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