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Slide Lecture Programs
2004 Core Curriculum
Impact of vascular biology on cardiovascular disease, risk prevention, and treatment
Section IV: RAAS manipulation and cardiovascular risk
August 27, 2004

E:  Risk reduction in diabetes: Focus on preclinical disease Slides 36 - 53

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36
  Slide: 36 - Risk reduction in diabetes: Focus on preclinical disease

Risk reduction in diabetes: Focus on preclinical disease
 
 
37
  Slide: 37 - Fatal/nonfatal CHD events in patients with/without history of MI or diabetes

Fatal/nonfatal CHD events in patients with/without history of MI or diabetes
 
 
38
  Slide: 38 - ↑ Carotid IMT precedes onset of type 2 diabetes

↑ Carotid IMT precedes onset of type 2 diabetes
 
 
39
  Slide: 39 - Impaired fibrinolytic function in metabolic syndrome

Impaired fibrinolytic function in metabolic syndrome
 
 
40
  Slide: 40 - NHANES III: Association of metabolic syndrome and chronic kidney disease

NHANES III: Association of metabolic syndrome and chronic kidney disease
 
 
41
  Slide: 41 - LIFE: Continuous relation of albuminuria to primary outcome <br>in patients with diabetes

LIFE: Continuous relation of albuminuria to primary outcome
in patients with diabetes
 
 
42
  Slide: 42 - Leukocyte Ang II: Evidence for association with insulin resistance

Leukocyte Ang II: Evidence for association with insulin resistance
 
 
43
  Slide: 43 - Prediabetic states: Links to subclinical atherosclerosis

Prediabetic states: Links to subclinical atherosclerosis
 
 
44
  Slide: 44 - Increased RAAS activity in diabetic nephropathy

Increased RAAS activity in diabetic nephropathy
 
 
45
  Slide: 45 - NF- kB activation in diabetic nephropathy

NF- kB activation in diabetic nephropathy
 
 
46
  Slide: 46 - Glucose activates renal RAAS in concentration-dependent manner

Glucose activates renal RAAS in concentration-dependent manner
 
 
47
  Slide: 47 - HOPE: Risk reduction is independent of diabetes or renal insufficiency

HOPE: Risk reduction is independent of diabetes or renal insufficiency
 
 
48
  Slide: 48 - Effect of ARBs in patients with type 2 diabetes and nephropathy

Effect of ARBs in patients with type 2 diabetes and nephropathy
 
 
49
  Slide: 49 - IDNT: Effect of ARB on CV outcomes

IDNT: Effect of ARB on CV outcomes
 
 
50
  Slide: 50 - LIFE: Comparison of treatment effects in overall population <br>vs patients with diabetes

LIFE: Comparison of treatment effects in overall population
vs patients with diabetes
 
 
51
  Slide: 51 - RAAS and diabetic nephropathy: Proposed mechanisms

RAAS and diabetic nephropathy: Proposed mechanisms
 
 
52
  Slide: 52 - Antihypertensive agents and risk of diabetes

Antihypertensive agents and risk of diabetes
 
 
53
  Slide: 53 - HOPE/HOPE-TOO: Prevention of diabetes

HOPE/HOPE-TOO: Prevention of diabetes
 
 
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