|
|
 |
29 |
 |
| |

Issues in chronic myocardial ischemia treatment
|
|
 |
|
 |
|
 |
30 |
 |
| |

Stable CAD: Multiple treatment options
|
|
 |
|
 |
|
 |
31 |
 |
| |

SAFE-LIFE: Evaluation of intensive lifestyle intervention
|
|
 |
|
 |
|
 |
32 |
 |
| |

SAFE-LIFE: Reduction in angina at 1 year with intensive lifestyle intervention
|
|
 |
|
 |
|
 |
33 |
 |
| |

Chronic ischemic heart disease: Treatment gaps
|
|
 |
|
 |
|
 |
34 |
 |
| |

Novel anti-ischemic strategy
|
|
 |
|
 |
|
 |
35 |
 |
| |

Ranolazine clinical trial program
|
|
 |
|
 |
|
 |
36 |
 |
| |

Ranolazine clinical trial program in chronic stable angina
|
|
 |
|
 |
|
 |
37 |
 |
| |

MARISA, CARISA, ERICA main findings
|
|
 |
|
 |
|
 |
38 |
 |
| |

Challenges in selected populations: Experience with ranolazine
|
|
 |
|
 |
|
 |
39 |
 |
| |

Antianginal efficacy by gender
|
|
 |
|
 |
|
 |
40 |
 |
| |

Antianginal efficacy by gender
|
|
 |
|
 |
|
 |
41 |
 |
| |

Antianginal efficacy by age
|
|
 |
|
 |
|
 |
42 |
 |
| |

Antianginal efficacy by diabetes status
|
|
 |
|
 |
|
 |
43 |
 |
| |

CARISA: Reductions in A1C (diabetes substudy)
|
|
 |
|
 |
|
 |
44 |
 |
| |

Summary: Ranolazine in challenging populations
|
|
 |
|
 |
|
 |
45 |
 |
| |

ROLE: Long-term safety and tolerability in stable CAD patients
|
|
 |
|
 |
|
 |
46 |
 |
| |

MERLIN-TIMI 36: Study design
|
|
 |
|
 |
|
 |
47 |
 |
| |

MERLIN-TIMI 36: Effect on primary endpoint
|
|
 |
|
 |
|
 |
48 |
 |
| |

MERLIN-TIMI 36: Components of primary endpoint
|
|
 |
|
 |
|
 |
49 |
 |
| |

MERLIN-TIMI 36: Efficacy results in major subgroups
|
|
 |
|
 |
|
 |
50 |
 |
| |

MERLIN-TIMI 36: Primary arrhythmia endpoints
|
|
 |
|
 |
|
 |
51 |
 |
| |

MERLIN-TIMI 36: Reduction in VT lasting 8 beats or more
|
|
 |
|
 |
|
 |
52 |
 |
| |

MERLIN-TIMI 36: Incidence of VT = 8 beats or more in high-risk subgroups
|
|
 |
|
 |
|
 |
53 |
 |
| |

MERLIN-TIMI 36: Ventricular tachycardia events
|
|
 |
|
 |
|
 |
54 |
 |
| |

MERLIN-TIMI 36: Major safety outcomes
|
|
 |
|
 |
|
 |
55 |
 |
| |

MERLIN-TIMI 36: Sudden cardiac death by subgroup
|
|
 |
|
 |
|
 |
56 |
 |
| |

MERLIN-TIMI 36: Summary and implications
|
|
 |
|
 |
|
 |
57 |
 |
| |

Stable CAD: Multiple treatment options
|
|
 |
|
 |
|
|
|
 |
59 |
 |
| |

ACIP: Baseline characteristics
|
|
 |
|
 |
|
 |
60 |
 |
| |

ACIP: Two-year cumulative all-cause mortality rates for the treatment strategies
|
|
 |
|
 |
|
 |
61 |
 |
| |

SWISSI II: Study design
|
|
 |
|
 |
|
 |
62 |
 |
| |

SWISSI II: Baseline characteristics
|
|
 |
|
 |
|
 |
63 |
 |
| |

SWISSI II: Treatment effect on primary outcome
|
|
 |
|
 |
|
 |
64 |
 |
| |

ACIP, SWISSI II: Summary and implications
|
|
 |
|
 |
|
 |
65 |
 |
| |

COURAGE: Defining optimal care
|
|
 |
|
 |
|
 |
66 |
 |
| |

What is the definitive role of PCI in chronic angina and stable CAD?
|
|
 |
|
 |
|
 |
67 |
 |
| |

Patient expectations about elective PCI for stable CAD
|
|
 |
|
 |
|
|
|
 |
69 |
 |
| |

COURAGE: Lifestyle intervention and risk factor goals
|
|
 |
|
 |
|
 |
70 |
 |
| |

COURAGE: Pharmacologic therapy
|
|
 |
|
 |
|
 |
71 |
 |
| |

COURAGE: Baseline angiographic data
|
|
 |
|
 |
|
 |
72 |
 |
| |

COURAGE: Baseline angina
|
|
 |
|
 |
|
 |
73 |
 |
| |

COURAGE: Inducible ischemia at baseline
|
|
 |
|
 |
|
 |
74 |
 |
| |

COURAGE: Treatment effect on primary outcome
|
|
 |
|
 |
|
 |
75 |
 |
| |

COURAGE: Treatment effect on angina
|
|
 |
|
 |
|
 |
76 |
 |
| |

COURAGE: Treatment effect in CV and diabetes subgroups
|
|
 |
|
 |
|
 |
77 |
 |
| |

COURAGE: Change in quality-of-life scores
|
|
 |
|
 |
|
 |
78 |
 |
| |

COURAGE: Summary and implications
|
|
 |
|
 |
|
|